Activon Tube
100% Medical Grade Manuka honey

Product Description
Activon Tube, 100% Manuka honey with no additives. This wound filler will de-bride and de-slough, eliminate odors and provides a moist wound healing environment.
Activon Tube is ideal for debriding necrotic tissue. Activon Tube can be used as a wound filler for use in cavities, just irrigate with saline solution.
Activon Tube is ideal for debriding necrotic tissue. Activon Tube can be used as a wound filler for use in cavities, just irrigate with saline solution.
Use
Twist off cap, apply liberally to the wound bed to a minimum depth of 5mm and cover with an appropriate secondary dressing. Activon Tube is a single patient use only product.

Top tip
Initially you may experience high levels of exudate, this is perfectly normal and will decrease over time, therefore your secondary dressing of choice may initially need to be super absorbent, we recommend Eclypse.
Click here for Instructions For Use

Top tip
Initially you may experience high levels of exudate, this is perfectly normal and will decrease over time, therefore your secondary dressing of choice may initially need to be super absorbent, we recommend Eclypse.
Click here for Instructions For Use
Use
Twist off cap, apply liberally to the wound bed to a minimum depth of 5mm and cover with an appropriate secondary dressing. Activon Tube is a single patient use only product.

Top tip
Initially you may experience high levels of exudate, this is perfectly normal and will decrease over time, therefore your secondary dressing of choice may initially need to be super absorbent, we recommend Eclypse.
Click here for Instructions For Use

Top tip
Initially you may experience high levels of exudate, this is perfectly normal and will decrease over time, therefore your secondary dressing of choice may initially need to be super absorbent, we recommend Eclypse.
Click here for Instructions For Use
Indications
Activon Tube is ideal for debriding necrotic tissue; it’s ideal for topping up dressings where the honey is washed away or great for using directly into cavities. Honey can be washed away using normal saline solution. As honey is a natural product any remaining honey will not have any adverse effects.
Activon Tube may be applied to any wound but especially: Pressure ulcers, leg ulcers, diabetic ulcers, surgical wounds, burns, graft sites, cavity wounds or applied to a primary dressing.
Browse case studies using Activon Tube
Activon Tube may be applied to any wound but especially: Pressure ulcers, leg ulcers, diabetic ulcers, surgical wounds, burns, graft sites, cavity wounds or applied to a primary dressing.
Browse case studies using Activon Tube
Contra-indications
Although the honey is not absorbed into the blood stream, we advise monitoring the levels of patients with diabetes. Do not use if allergic to bee venom.
Discomfort can be experienced when honey is applied, depending on sensitivity of the wound it may be necessary to consider an appropriate level of analgesic. The initial discomfort usually subsides, however if it does continue, discontinue use and irrigate the wound with saline solution.
Discomfort can be experienced when honey is applied, depending on sensitivity of the wound it may be necessary to consider an appropriate level of analgesic. The initial discomfort usually subsides, however if it does continue, discontinue use and irrigate the wound with saline solution.
Ordering
Product | Size | Stock Code | Pack Size | HCPCS Code |
Activon Tube | Size: 0.9oz | Stock Code: CR3830 | Pack Size: 12 | HCPCS Code: A6250 |
Literature
Clinical evidence
- Activon Tube & Activon Tulle on venous leg ulcers - Ann Smith
- Activon Tube in the treatment of a diabetic patient - Catherine Gooday
- Activon Tulle in the treatment of a fungating tumour
- Activon Tulle on a diabetic patient with digital ulceration - Georgie Hollis
- Activon Tulle on a grade 3 pressure ulcer - Anita Kilroy-Findley
- Activon Tulle on a grade 4 pressure ulcer - Jill Hardman
- Activon Tulle on a venous ulcer - Georgina Preston
- Activon Tulle on extensive cellulitis - Pauline Morrison
- Antimicrobial activity of 3 honey impregnated wound dressings by challenge test with EMRSA-15
- Barry Noble - ISBI 2012 Poster
- Do Honey dressing reduce the need for antibiotics? - Perry & O'Hara
- Evaluation of 100% Manuka honey in expedience of diabetic wound healing... by Diane Heasley
- Evaluation of a 100% Manuka honey in the debridement of diabetic foot ulcers...Melissa Barcic, Diane Heasley
- Evaluation of a 100% Medical Grade Manuka honey in expedience of diabetic wound debridement versus a selective chemical debriding agent- Diane Heasley
- Evaluation of a Honey dressing on wounds within Primary Care - Jackie Stephen-Haynes et al
- Evaluation of a knitted viscose mesh dressing impregnated with 100% Medical Grade Manuka honey & it's management wound odor vs an antimicrobial spray & a carbon based dressing
- Evaluation of expedience in the debridement of diabetic ulcers... Diane Heasley & Brittany Robinson
- Evaluation of expedience of infected wound healing using a viscose mesh impregnated with 100% Medical Grade Manuka honey versus a silver hydrogel sheet- Diane Heasley
- Evaluation of the expedience of the healing of tunneled wounds... Melissa Barcic
- Evaluation of the Stabilization & Expedience in healing of skin tears... Diane Heasley
- Evaluation of the use of 100%preservative & coloration free Manuka honey in the treatment of Tinea Pedis- Diane Heasley
- Expedience of debridement & cost comparison of pressure ulcer debridement utilizing a 100% preservative free/ coloration free Manuka honey vs a selective chemical debrider
- Is Honey the Bees’ Knees? - Ailsa Sharp et al
- Jacky Edwards - ISBI 2012 Poster
- Various case studies using Activon Honey
External Resources
Honey as a topical antibacterial agent for treatment of infected wounds.
Molan. P December 2001
Healing of an MRSA-Colonized, hydroxyurea induced leg ulcer with Honey. Journal of Dermatological Treatment (2001) 12, 33-66
S Natarajan, D Williamson, J Grey, KG Harding and RA Cooper (2001)
The use of honey in wound management. Nursing Standard, 15,11,63-68 November 2000
Dunford C et al (2000)
Odour Absorbing Dressings: A comparative laboratory study.
Thomas P 1998 April 1998
A survey of the antibacterial activity of some New Zealand honeys. J Pharm Pharmacol 1991; 43(12): 817-22.
Allen KL, Molan PC, Reid GM.
Molan. P December 2001
Healing of an MRSA-Colonized, hydroxyurea induced leg ulcer with Honey. Journal of Dermatological Treatment (2001) 12, 33-66
S Natarajan, D Williamson, J Grey, KG Harding and RA Cooper (2001)
The use of honey in wound management. Nursing Standard, 15,11,63-68 November 2000
Dunford C et al (2000)
Odour Absorbing Dressings: A comparative laboratory study.
Thomas P 1998 April 1998
A survey of the antibacterial activity of some New Zealand honeys. J Pharm Pharmacol 1991; 43(12): 817-22.
Allen KL, Molan PC, Reid GM.
FAQ
- 1. Can Activon honey be used under compression bandaging?
- The Activon range can be used under compression bandaging. The amount of exudate would influence your choice of Activon Tulle or Actilite with an appropriate absorbent secondary dressing such as Eclypse. The secondary dressing must be appropriate to the exudate level and will influence wear time.
- 2. Can Activon Tulle be folded and put into a cavity?
- Activon Tulle dressings can be put into a cavity wound, again dependant on exudate levels. If there is a possibility of sinus within the wound base then Activon Tube should be used to ensure that the honey reaches the entire wound bed.
- 3. Can the Activon Tulle be unfolded to apply?
- Activon Tulle can be unfolded and applied, however this will reduce the level of honey at the wound bed. The triple layer of the gauze delivers the optimum amount of honey to the wound bed therefore unfolding the dressing would affect efficacy.
- 4. Can your Manuka honey dressings be used on diabetic patients?
- While there is no known case of honey influencing blood glucose levels adversely, it is recommended that the blood sugar levels of patients with diabetes are monitored when using honey.
- 5. Does the honey sting on application?
- There have been reports of honey causing a stinging pain when applied to the wound. This appears to be due to the acidity of honey, as pain is not experienced when neutralised honey is used. The pain experienced does not seem to be indicative of damage being done to the wound, as wounds have healed rapidly in cases where patients have endured the pain to benefit from the stimulation of healing that they see, and in cases where analgesia has been used.
There is evidence that honey stimulates nocioceptors (Al-Swayeh and Ali, 1998), nerve endings that create a pain sensation in response to heat, acidity and some organic chemicals. It may be that it is not a direct effect of the acidity of honey, as neutralising honey could affect the ionisation of some of its components and make them unable to fit in the nocioceptors. It is possible that in some patients these nerve endings are sensitised and are more responsive to the acidity and/or the component organic chemicals of honey. - 6. How long can the honey dressings be left on the wound for?
- The dressings can be left in place for up to seven days, again this would depend on the exudate levels produced by the wound and the appearance of the dressing. As long as the dressing has maintained it’s original colour (the honey is present) it can remain in situ.
- 7. What are the contra indications for your Manuka honey?
- Known allergy to bee-venom. Although no known instance of increased levels of blood sugar in patients with diabetes. It is advisable to closely monitor the levels. Increased pain may be experienced due to acidification.
- 8. What secondary dressing do you recommend?
- It depends upon the level of exudate. Low to moderate exuding wounds
we recommend the Advazorb® range of foam dressings. For medium to
high exudate, we recommend Eclypse® super absorbent dressings. - 9. Do honey dressings increase wound exudate levels?
- Yes, this is due to osmotic action which is an important and integral
part of how honey works. Ensure secondary dressing can cope with the
increased exudate level. The high level of exudate should subside after
time.